One of the hot topics that has recently come to light, or rather should be a hot topic is that of Alzheimer's Disease. Now this disease is marked by the loss of memory and eventual motor controls, it even goes so far as to make you forget how to breathe. As we all know, breathing tends to be very important to the living human, without it, well we don't live very long.
Now Alzheimer's is caused by the build up of plaques and tangles, they are caused by a build up of amyloid-β and the tau protein respectively. The amyloid-β protein builds up outside the neuron cell while the tau protein builds up inside the neuron cell, and eventually both of these kill off neurons and dendrites, basically severing the neural pathways.
Recently though, as in August of 2012, scientists may have found something that could help in the prevention, and possibly even the reversal of buildup caused by plaques and tangles. Basically the brain is not attached to the lymphatic system so it doesn't go through a normal cleaning process like the rest of the brain (see picture below). Instead what happens it that the cerebrospinal fluid enters the arteries of the brain and then flow through the brain tissue, as it moves along it gathers any particles of debris and once it reaches the vein everything can be transported out of the brain.
Now what scientists are hoping for is to find a way to increase the flow of this system thereby increasing the amount of debris that can be removed possibly aiding in the fight against Alzheimer's. Of course this research is not only limited to Alzheimer's treatment but it can be applied to other diseases that are caused by similar buildups in the brain.
Hopefully soon there will be real treatment for this terrible disease, who knows maybe there'll be a cure. Take a look at the video below to see a researcher describe their findings, basically I just summarized what he will say.
Great blog topic! My favorite topic, as you may well know. I had actually read about that type of prevention but I had never really looked into it. It’s so interesting though and it would be a great way to prevent Alzheimer’s. I also like the way you named your blog. “Cleaning the Brain”. This is a great title because essentially this is what is happening. The cerebrospinal fluid is cleaning the brain and getting rid of toxins and well any debris that is causing major damage. I hope to learn more about this topic and I hope they actually figure out all the kinks I’m sure it has so they can use it to successfully prevent Alzheimer’s disease.
ReplyDeleteVery interesting! I recently became aware of the severity of Alzheimer's disease. I wasn't aware that it could even cause people to forget how to breath. Its crazy to think about that. Breathing is something we naturally know how to do. No one has to teach us to breath in and out. Its a natural instinct. For Alzheimer's to be able to violate that is crazy.
ReplyDeleteIt would be amazing if essentially the brain in this victims could be "cleaned up" by removing the debris that have build up. As I mentioned in my blog, my grandmother suffered with Alzheimer's and it was something very sad to have to witness. With the advances in technology that we are going through hopefully one day Alzheimer's can be checked off the list of diseases without a cure.
I'm VERY excited to find out more about this discovery you mentioned about! :)
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